4. LbL Assembled Micro/Nanostructures

The assembly of multifunctional biomimetic microcapsules/spheres at the molecular level is of tremendous interest for biophysical research and the biomedical field. LbL assembly has been extensively used to fabricate hollow multifunctionalized microcapsules/spheres since it allows an unprecedented variety of materials to be assembled into microcapsules/spheres using simple, controllable, inexpensive procedures. Our group has achieve great progress on LbL-assembled biomimetic microcapsule fabricated by applying polysaccharides and proteins as assembly units. These biomimetic microcapsules have been applied in drug delivery, blood substitutes and other biomedical fields. Chem. Rev. 2015, 115, 1597; Chem. Eur. J. 2015, 21, 520; Chem. Commun. 2013, 49, 10733; ACS Nano 2012, 6, 10910; Adv. Funct. Mater. 2012, 22, 2673; Adv. Funct. Mater. 2012, 22, 1446; ACS Nano 2012, 6, 6897; Chem. Soc. Rev. 2009, 38, 2292; Adv. Mater. 2008, 20, 2933; Angew. Chem. Int. Ed. 2007, 46, 6996.

Glucose-sensitive Microcapsules from Glutaraldehyde Cross-linked Hemoglobin and Glucose Oxidase

pH and Redox-responsive Polysaccharide-based Microcapsules for Cancer Therapy

Bioluminescent Microcapsules: Applications in Activating a Photosensitizer

Construction and Evaluation of Hemoglobin-Based Capsules as Blood Substitutes

Highly Loaded Hemoglobin Spheres as Promising Artificial Oxygen Carriers